Cyclophilin A protects mice against infection by influenza A virus

Our previous studies indicate that Cyclophilin A (CypA) impairs the replication of influenza A virus in vitro. To further evaluate the antiviral functions of CypA and explore its mechanism, transgenic mice with overexpression of CypA by two specific promoters with SPC (CypA-SPC) or CMV (CypA-CMV) we...

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Published in:Sci Rep
Main Authors: Li, Jing, Chen, Can, Wong, Gary, Dong, Wei, Zheng, Weinan, Li, Yun, Sun, Lei, Zhang, Lianfeng, Gao, George F., Bi, Yuhai, Liu, Wenjun
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4926061/
https://ncbi.nlm.nih.gov/pubmed/27354005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28978
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