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Cortical amyloid burden and age moderate hippocampal activity in cognitively-normal adults
Neurodegeneration in the medial temporal lobe, particularly in the hippocampus, is viewed as the primary source of AD-related memory deficits. Yet, in the earliest preclinical phase of Alzheimer's disease (AD), amyloid-beta (Aβ) plaques deposit primarily in the neocortex, not in the medial temp...
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| Опубликовано в: : | Neuroimage Clin |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4925884/ https://ncbi.nlm.nih.gov/pubmed/27408792 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2016.05.013 |
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