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Sex-specific effects of cytotoxic chemotherapy agents cyclophospha-mide and mitomycin C on gene expression, oxidative DNA damage, and epigenetic alterations in the prefrontal cortex and hippocampus – an aging connection

Recent research shows that chemotherapy agents can be more toxic to healthy brain cells than to the target cancer cells. They cause a range of side effects, including memory loss and cognitive dysfunction that can persist long after the completion of treatment. This condition is known as chemo brain...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Kovalchuk, Anna, Rodriguez-Juarez, Rocio, Ilnytskyy, Yaroslav, Byeon, Boseon, Shpyleva, Svitlana, Melnyk, Stepan, Pogribny, Igor, Kolb, Bryan, Kovalchuk, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4925823/
https://ncbi.nlm.nih.gov/pubmed/27032448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.100920
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