Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice

5XFAD is an early-onset mouse transgenic model of Alzheimer disease (AD). Up to now there are no studies that focus on the epigenetic changes produced as a result of Aβ-42 accumulation and the possible involvement in the different expression of related AD-genes. Under several behavioral and cognitio...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Griñán-Ferré, Christian, Sarroca, Sara, Ivanova, Aleksandra, Puigoriol-Illamola, Dolors, Aguado, Fernando, Camins, Antoni, Sanfeliu, Coral, Pallàs, Mercè
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4925821/
https://ncbi.nlm.nih.gov/pubmed/27013617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.100906
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