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PrEP adherence patterns strongly impact individual HIV risk and observed efficacy in randomized clinical trials

BACKGROUND: Randomized controlled trials (RCT) suggest that the efficacy of tenofovir-based pre-exposure prophylaxis (PrEP) strongly depends on consistency of PrEP use. We explore how patterns of pill-taking and waning of PrEP protection may affect PrEP efficacy for HIV prevention. METHODS: A two-ar...

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Detalhes bibliográficos
Publicado no:J Acquir Immune Defic Syndr
Main Authors: DIMITROV, Dobromir T., MÂSSE, Benoît R., DONNELL, Deborah
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4925182/
https://ncbi.nlm.nih.gov/pubmed/26990823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000000993
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