Solvent dielectric effects on protein dynamics.

Electron paramagnetic resonance (EPR) spectroscopy and molecular dynamics (MD) simulations were used to investigate the dynamics of alpha-chymotrypsin in solvents ranging in dielectric constant from 72 to 1.9. EPR measurements showed that motions in the vicinity of two spin-labeled amino acids (Met-...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Affleck, R, Haynes, C A, Clark, D S
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49250/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1317584/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.11.5167
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