Rhodopsin kinase and arrestin binding control the decay of photoactivated rhodopsin and dark adaptation of mouse rods

Photoactivation of vertebrate rhodopsin converts it to the physiologically active Meta II (R*) state, which triggers the rod light response. Meta II is rapidly inactivated by the phosphorylation of C-terminal serine and threonine residues by G-protein receptor kinase (Grk1) and subsequent binding of...

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Veröffentlicht in:J Gen Physiol
Hauptverfasser: Frederiksen, Rikard, Nymark, Soile, Kolesnikov, Alexander V., Berry, Justin D., Adler, Leopold, Koutalos, Yiannis, Kefalov, Vladimir J., Cornwall, M. Carter
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2016
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924931/
https://ncbi.nlm.nih.gov/pubmed/27353443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201511538
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