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Influence of Matrices on 3D-Cultured Prostate Cancer Cells' Drug Response and Expression of Drug-Action Associated Proteins

This study investigated the effects of matrix on the behaviors of 3D-cultured cells of two prostate cancer cell lines, LNCaP and DU145. Two biologically-derived matrices, Matrigel and Cultrex BME, and one synthetic matrix, the Alvetex scaffold, were used to culture the cells. The cell proliferation...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Edmondson, Rasheena, Adcock, Audrey F., Yang, Liju
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924873/
https://ncbi.nlm.nih.gov/pubmed/27352049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158116
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