Cardiac myosin-Th17 responses promote heart failure in human myocarditis

In human myocarditis and its sequela dilated cardiomyopathy (DCM), the mechanisms and immune phenotype governing disease and subsequent heart failure are not known. Here, we identified a Th17 cell immunophenotype of human myocarditis/DCM with elevated CD4(+)IL17(+) T cells and Th17-promoting cytokin...

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Vydáno v:JCI Insight
Hlavní autoři: Myers, Jennifer M., Cooper, Leslie T., Kem, David C., Stavrakis, Stavros, Kosanke, Stanley D., Shevach, Ethan M., Fairweather, DeLisa, Stoner, Julie A., Cox, Carol J., Cunningham, Madeleine W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924810/
https://ncbi.nlm.nih.gov/pubmed/27366791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.85851
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