HULC long noncoding RNA silencing suppresses angiogenesis by regulating ESM-1 via the PI3K/Akt/mTOR signaling pathway in human gliomas

Tumor angiogenesis plays a critical role in the tumor progression. Highly upregulated in liver cancer (HULC) is a long noncoding RNA (lncRNA) that acts as an oncogene in gliomas. We found that HULC, vascular endothelial growth factor (VEGF), and ESM-1 (endothelial cell specific molecule 1) expressio...

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Udgivet i:Oncotarget
Main Authors: Zhu, Yu, Zhang, Xuebin, Qi, Lisha, Cai, Ying, Yang, Ping, Xuan, Geng, Jiang, Yuan
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924726/
https://ncbi.nlm.nih.gov/pubmed/26894862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7418
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