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RACK1 overexpression is linked to acquired imatinib resistance in gastrointestinal stromal tumor
Although treatment with imatinib, which inhibits KIT and PDGFR, controls advanced disease in about 80% of gastrointestinal stromal tumor (GIST) patients, resistance to imatinib often develops. RACK1 (Receptor for Activated C Kinase 1) is a ribosomal protein that contributes to tumor progression by a...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4924716/ https://ncbi.nlm.nih.gov/pubmed/26893362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7426 |
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