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Distinct features between MLH1-methylated and unmethylated colorectal carcinomas with the CpG island methylator phenotype: implications in the serrated neoplasia pathway

The presence or absence of MLH1 methylation may critically affect the heterogeneity of colorectal carcinoma (CRC) with the CpG island methylator phenotype (CIMP). Here, we investigated the differential characteristics of CIMP-high (CIMP-H) CRCs according to MLH1 methylation status. To further confir...

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Vydáno v:Oncotarget
Hlavní autoři: Kim, Jung Ho, Bae, Jeong Mo, Cho, Nam-Yun, Kang, Gyeong Hoon
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924700/
https://ncbi.nlm.nih.gov/pubmed/26883113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7374
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