Targeting endothelial connexin40 inhibits tumor growth by reducing angiogenesis and improving vessel perfusion

Endothelial connexin40 (Cx40) contributes to regulate the structure and function of vessels. We have examined whether the protein also modulates the altered growth of vessels in tumor models established in control mice (WT), mice lacking Cx40 (Cx40−/−), and mice expressing the protein solely in endo...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Alonso, Florian, Domingos-Pereira, Sonia, Le Gal, Loïc, Derré, Laurent, Meda, Paolo, Jichlinski, Patrice, Nardelli-Haefliger, Denise, Haefliger, Jacques-Antoine
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924695/
https://ncbi.nlm.nih.gov/pubmed/26883111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7370
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