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Targeting endothelial connexin40 inhibits tumor growth by reducing angiogenesis and improving vessel perfusion

Endothelial connexin40 (Cx40) contributes to regulate the structure and function of vessels. We have examined whether the protein also modulates the altered growth of vessels in tumor models established in control mice (WT), mice lacking Cx40 (Cx40−/−), and mice expressing the protein solely in endo...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Alonso, Florian, Domingos-Pereira, Sonia, Le Gal, Loïc, Derré, Laurent, Meda, Paolo, Jichlinski, Patrice, Nardelli-Haefliger, Denise, Haefliger, Jacques-Antoine
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924695/
https://ncbi.nlm.nih.gov/pubmed/26883111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7370
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