Prognostic and therapeutic role of targetable lesions in B-lineage acute lymphoblastic leukemia without recurrent fusion genes

To shed light into the molecular bases of B-lineage acute lymphoblastic leukemia lacking known fusion transcripts, i.e. BCR-ABL1, ETV6-RUNX1, E2A-PBX1, and MLL rearrangements (B-NEG ALL) and the differences between children, adolescents/young adults (AYA) and adults, we analyzed 168 B-NEG ALLs by ge...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Messina, Monica, Chiaretti, Sabina, Wang, Jiguang, Fedullo, Anna Lucia, Peragine, Nadia, Gianfelici, Valentina, Piciocchi, Alfonso, Brugnoletti, Fulvia, Di Giacomo, Filomena, Pauselli, Simona, Holmes, Antony B., Puzzolo, Maria Cristina, Ceglie, Giulia, Apicella, Valerio, Mancini, Marco, te Kronnie, Geertruy, Testi, Anna Maria, Vitale, Antonella, Vignetti, Marco, Guarini, Anna, Rabadan, Raul, Foà, Robin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924686/
https://ncbi.nlm.nih.gov/pubmed/26883104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7356
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