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Enzymatic Macrocyclization of 1,2,3‐Triazole Peptide Mimetics

The macrocyclization of linear peptides is very often accompanied by significant improvements in their stability and biological activity. Many strategies are available for their chemical macrocyclization, however, enzyme‐mediated methods remain of great interest in terms of synthetic utility. To dat...

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Vydáno v:Angew Chem Int Ed Engl
Hlavní autoři: Oueis, Emilia, Jaspars, Marcel, Westwood, Nicholas J., Naismith, James H.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924597/
https://ncbi.nlm.nih.gov/pubmed/27059105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201601564
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