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Effects of inhibitors of vascular endothelial growth factor receptor 2 and downstream pathways of receptor tyrosine kinases involving phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin or mitogen-activated protein kinase in canine hemangiosarcoma cell lines

Canine hemangiosarcoma (HSA) is a progressive malignant neoplasm with no current effective treatment. Previous studies showed that receptor tyrosine kinases and molecules within their downstream pathways involving phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (m-TOR) or mito...

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Bibliographische Detailangaben
Veröffentlicht in:Can J Vet Res
Hauptverfasser: Adachi, Mami, Hoshino, Yuki, Izumi, Yusuke, Sakai, Hiroki, Takagi, Satoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Canadian Veterinary Medical Association 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924555/
https://ncbi.nlm.nih.gov/pubmed/27408334
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