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Nanoparticle delivery of miR-223 to attenuate macrophage fusion

The foreign body response (FBR) begins with injury acquired during implantation of a biomaterial (BM) and is detrimental due to the eventual encapsulation of the implant. Fusion of macrophages to form foreign body giant cells (FBGC), a hallmark of the FBR, is the consequence of a multistep mechanism...

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Détails bibliographiques
Publié dans:Biomaterials
Auteurs principaux: Moore, Laura Beth, Sawyer, Andrew J., Saucier-Sawyer, Jennifer, Saltzman, W. Mark, Kyriakides, Themis R.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924476/
https://ncbi.nlm.nih.gov/pubmed/26967647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.02.036
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