Development and characterization of an in vitro model of colorectal adenocarcinoma with MDR phenotype

The major cause of failure in cancer chemotherapy is the development of multidrug resistance (MDR), and the characterization of biological factors involved in this response to therapy is particularly needed. A doxorubicin‐resistant HCT‐8/R clone was selected from sensitive parental cells and charact...

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Vydáno v:Cancer Med
Hlavní autoři: Cinci, Lorenzo, Luceri, Cristina, Bigagli, Elisabetta, Carboni, Ilaria, Paccosi, Sara, Parenti, Astrid, Guasti, Daniele, Coronnello, Marcella
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2016
Témata:
Cancer Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924386/
https://ncbi.nlm.nih.gov/pubmed/27016279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.694
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