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5-azacytidine induces transcriptome changes in Escherichia coli via DNA methylation-dependent and DNA methylation-independent mechanisms

BACKGROUND: Escherichia coli K-12 strains contain DNA cytosine methyltransferase (Dcm), which generates 5-methylcytosine at 5′CCWGG3′ sites. Although the role of 5-methylcytosine in eukaryotic gene expression is relatively well described, the role of 5-methylcytosine in bacterial gene expression is...

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Detalhes bibliográficos
Publicado no:BMC Microbiol
Main Authors: Militello, Kevin T., Simon, Robert D., Mandarano, Alexandra H., DiNatale, Anthony, Hennick, Stacy M., Lazatin, Justine C., Cantatore, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924334/
https://ncbi.nlm.nih.gov/pubmed/27349222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-016-0741-4
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