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Intratumoral heterogeneity as a source of discordance in breast cancer biomarker classification

BACKGROUND: Spatial heterogeneity in biomarker expression may impact breast cancer classification. The aims of this study were to estimate the frequency of spatial heterogeneity in biomarker expression within tumors, to identify technical and biological factors contributing to spatial heterogeneity,...

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Bibliografiska uppgifter
I publikationen:Breast Cancer Res
Huvudupphovsmän: Allott, Emma H., Geradts, Joseph, Sun, Xuezheng, Cohen, Stephanie M., Zirpoli, Gary R., Khoury, Thaer, Bshara, Wiam, Chen, Mengjie, Sherman, Mark E., Palmer, Julie R., Ambrosone, Christine B., Olshan, Andrew F., Troester, Melissa A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924300/
https://ncbi.nlm.nih.gov/pubmed/27349894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-016-0725-1
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