Frequency of BRAF V600E mutations in 969 central nervous system neoplasms

BACKGROUND: Treatment options for oncological diseases have been enhanced by the advent of targeted therapies. The point mutation of the BRAF gene at codon 600 (BRAF V600E) is found in several tumor entities and can be approached with selective inhibitory antibodies. The BRAF inhibitor vemurafenib h...

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Detalhes bibliográficos
Publicado no:Diagn Pathol
Main Authors: Behling, Felix, Barrantes-Freer, Alonso, Skardelly, Marco, Nieser, Maike, Christians, Arne, Stockhammer, Florian, Rohde, Veit, Tatagiba, Marcos, Hartmann, Christian, Stadelmann, Christine, Schittenhelm, Jens
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4924254/
https://ncbi.nlm.nih.gov/pubmed/27350555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-016-0506-2
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