Pubertal development in healthy children is mirrored by DNA methylation patterns in peripheral blood

Puberty marks numerous physiological processes which are initiated by central activation of the hypothalamic–pituitary–gonadal axis, followed by development of secondary sexual characteristics. To a large extent, pubertal timing is heritable, but current knowledge of genetic polymorphisms only expla...

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Udgivet i:Sci Rep
Main Authors: Almstrup, Kristian, Lindhardt Johansen, Marie, Busch, Alexander S., Hagen, Casper P., Nielsen, John E., Petersen, Jørgen Holm, Juul, Anders
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4923870/
https://ncbi.nlm.nih.gov/pubmed/27349168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28657
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