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Clinical relevance between CALR mutation and myeloproliferative neoplasms

In late 2013, somatic mutations in calreticulin (CALR), mainly those involving insertions and deletions in exon 9, attracted the great attention of hematologists and researchers. These JAK2- and MPL- mutual exclusive mutations enjoy a favorable specificity and prevalence (20-30%) in patients with es...

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Pubblicato in:Stem Cell Investig
Autori principali: Wu, Zhiyuan, Zhang, Chen, Ma, Xiaochao, Guan, Ming
Natura: Artigo
Lingua:Inglês
Pubblicazione: AME Publishing Company 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4923639/
https://ncbi.nlm.nih.gov/pubmed/27358872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2306-9759.2015.01.03
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