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Regulatory factors of induced pluripotency: current status

Somatic cells can be reprogrammed to induced pluripotent stem cells (iPSCs) through enforced expression of four transcription factors [Oct4, Sox2, Klf4, and c-Myc (OSKM)]; however, the reprogramming efficiency is extremely low. This finding raises fundamental questions about the regulators that infl...

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Bibliographische Detailangaben
Veröffentlicht in:Stem Cell Investig
Hauptverfasser: Zhao, Wei, Ning, Bo, Qian, Chen
Format: Artigo
Sprache:Inglês
Veröffentlicht: AME Publishing Company 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4923514/
https://ncbi.nlm.nih.gov/pubmed/27358861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2306-9759.2014.07.01
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