BRCA1 and BRCA2 sequence variations detected with next-generation sequencing in patients with premature ovarian insufficiency

OBJECTIVE: Although the association between BRCA1 and BRCA2 gene mutations and breast and ovarian cancer is known, there is insufficient data about premature ovarian insufficiency (POI). However, several studies have reported that there might be a relationship between POI and BRCA1 and BRCA2 gene mu...

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Bibliografiske detaljer
Udgivet i:J Turk Ger Gynecol Assoc
Main Authors: Yılmaz, Nafiye Karakaş, Karagin, Peren Hatice, Terzi, Yunus Kasım, Kahyaoğlu, İnci, Yılmaz, Saynur, Erkaya, Salim, Şahin, Feride İffet
Format: Artigo
Sprog:Inglês
Udgivet: AVES 2016
Fag:
Original Investigation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922729/
https://ncbi.nlm.nih.gov/pubmed/27403073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5152/jtgga.2016.16035
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