CKAP4 is a Dickkopf1 receptor and is involved in tumor progression

Dickkopf1 (DKK1) is a secretory protein that antagonizes oncogenic Wnt signaling by binding to the Wnt coreceptor low-density lipoprotein receptor–related protein 6 (LRP6). DKK1 may also regulate its own signaling to promote cancer cell proliferation, but the mechanism is not understood. Here, we id...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Kimura, Hirokazu, Fumoto, Katsumi, Shojima, Kensaku, Nojima, Satoshi, Osugi, Yoshihito, Tomihara, Hideo, Eguchi, Hidetoshi, Shintani, Yasushi, Endo, Hiroko, Inoue, Masahiro, Doki, Yuichiro, Okumura, Meinoshin, Morii, Eiichi, Kikuchi, Akira
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922689/
https://ncbi.nlm.nih.gov/pubmed/27322059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI84658
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