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Microbial peptide de-coppers mitochondria: implications for Wilson disease
The severe liver pathology of untreated Wilson disease (WD) is associated with massive copper overload caused by mutations in a liver-specific copper-transporting ATPase, ATP7B. While early, presymptomatic detection and chelation with conventional copper-binding molecules enables effective and life-...
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| Publicado no: | J Clin Invest |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4922682/ https://ncbi.nlm.nih.gov/pubmed/27322063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI88617 |
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