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Copper Exposure Perturbs Brain Inflammatory Responses and Impairs Clearance of Amyloid-Beta
Copper promotes a toxic buildup of amyloid-beta (Aβ) and neurofibrillary tangle pathology in the brain, and its exposure may increase the risk for Alzheimer’s disease (AD). However, underlying molecular mechanisms by which copper triggers such pathological changes remain largely unknown. We hypothes...
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| Publicado no: | Toxicol Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4922545/ https://ncbi.nlm.nih.gov/pubmed/27122238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw081 |
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