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Copper Exposure Perturbs Brain Inflammatory Responses and Impairs Clearance of Amyloid-Beta
Copper promotes a toxic buildup of amyloid-beta (Aβ) and neurofibrillary tangle pathology in the brain, and its exposure may increase the risk for Alzheimer’s disease (AD). However, underlying molecular mechanisms by which copper triggers such pathological changes remain largely unknown. We hypothes...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Toxicol Sci |
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| Κύριοι συγγραφείς: | , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4922545/ https://ncbi.nlm.nih.gov/pubmed/27122238 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw081 |
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