Metallothionein MT2A A-5G Polymorphism as a Risk Factor for Chronic Kidney Disease and Diabetes: Cross-Sectional and Cohort Studies

Metallothioneins (MTs) are proteins that protect cells from toxic agents such as heavy metal ions or reactive oxygen species. MT2A A-5G is a single nucleotide polymorphism in the promoter region of the MT2A gene, and the minor G allele results in lower transcription efficiency. We aimed to elucidate...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Hattori, Yuta, Naito, Mariko, Satoh, Masahiko, Nakatochi, Masahiro, Naito, Hisao, Kato, Masashi, Takagi, Sahoko, Matsunaga, Takashi, Seiki, Toshio, Sasakabe, Tae, Suma, Shino, Kawai, Sayo, Okada, Rieko, Hishida, Asahi, Hamajima, Nobuyuki, Wakai, Kenji
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Metallothionein Polymorphisms in Diabetes and Renal Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922544/
https://ncbi.nlm.nih.gov/pubmed/27122239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfw080
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