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BRAF-directed Therapy in Metastatic Colorectal Cancer

Activating BRAF mutations occur in approximately 5–10% of metastatic colorectal cancer (mCRC) patients, mostly V600E mutation, and it is associated with distinct clinical and pathological features. To date, there are no approved treatments to target this mutation. BRAF inhibitor monotherapy has limi...

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Bibliografski detalji
Izdano u:Cancer J
Glavni autori: Korphaisarn, Krittiya, Kopetz, Scott
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922502/
https://ncbi.nlm.nih.gov/pubmed/27341594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000189
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