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BRAF-directed Therapy in Metastatic Colorectal Cancer

Activating BRAF mutations occur in approximately 5–10% of metastatic colorectal cancer (mCRC) patients, mostly V600E mutation, and it is associated with distinct clinical and pathological features. To date, there are no approved treatments to target this mutation. BRAF inhibitor monotherapy has limi...

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Foilsithe in:Cancer J
Main Authors: Korphaisarn, Krittiya, Kopetz, Scott
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922502/
https://ncbi.nlm.nih.gov/pubmed/27341594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PPO.0000000000000189
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