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Immune recruitment or suppression by glycan engineering of endogenous and therapeutic antibodies()

Human serum IgG contains multiple glycoforms which exhibit a range of binding properties to effector molecules such as cellular Fc receptors. Emerging knowledge of how the Fc glycans contribute to the antibody structure and effector functions has opened new avenues for the exploitation of defined an...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Le, Ngoc Phuong Lan, Bowden, Thomas A., Struwe, Weston B., Crispin, Max
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Pub. Co 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922387/
https://ncbi.nlm.nih.gov/pubmed/27105835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagen.2016.04.016
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