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Reactivation of HIV latency by a newly modified Ingenol derivative via protein kinase Cδ–NF-κB signaling

OBJECTIVE: Although HAART effectively suppresses viral replication, it fails to eradicate latent viral reservoirs. The ‘shock and kill’ strategy involves the activation of HIV from latent reservoirs and targeting them for eradication. Our goal was to develop new approaches for activating HIV from la...

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Библиографические подробности
Опубликовано в: :	AIDS
Главные авторы:	Jiang, Guochun, Mendes, Erica A., Kaiser, Philipp, Sankaran-Walters, Sumathi, Tang, Yuyang, Weber, Mariana G., Melcher, Greg P., Thompson, George R., Tanuri, Amilcar, Pianowski, Luiz F., Wong, Joseph K., Dandekar, Satya
Формат:	Artigo
Язык:	Inglês
Опубликовано:	2014
Предметы:	Article
Online-ссылка:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4922310/ https://ncbi.nlm.nih.gov/pubmed/24804860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000000289
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Reactivation of HIV latency by a newly modified Ingenol derivative via protein kinase Cδ–NF-κB signaling

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