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Reactivation of HIV latency by a newly modified Ingenol derivative via protein kinase Cδ–NF-κB signaling
OBJECTIVE: Although HAART effectively suppresses viral replication, it fails to eradicate latent viral reservoirs. The ‘shock and kill’ strategy involves the activation of HIV from latent reservoirs and targeting them for eradication. Our goal was to develop new approaches for activating HIV from la...
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| Pubblicato in: | AIDS |
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| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4922310/ https://ncbi.nlm.nih.gov/pubmed/24804860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000000289 |
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