Reactivation of HIV latency by a newly modified Ingenol derivative via protein kinase Cδ–NF-κB signaling

OBJECTIVE: Although HAART effectively suppresses viral replication, it fails to eradicate latent viral reservoirs. The ‘shock and kill’ strategy involves the activation of HIV from latent reservoirs and targeting them for eradication. Our goal was to develop new approaches for activating HIV from la...

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Publicado en:AIDS
Autores principales: Jiang, Guochun, Mendes, Erica A., Kaiser, Philipp, Sankaran-Walters, Sumathi, Tang, Yuyang, Weber, Mariana G., Melcher, Greg P., Thompson, George R., Tanuri, Amilcar, Pianowski, Luiz F., Wong, Joseph K., Dandekar, Satya
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922310/
https://ncbi.nlm.nih.gov/pubmed/24804860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0000000000000289
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