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LAP-like process as an immune mechanism downstream of IFN-γ in control of the human malaria Plasmodium vivax liver stage

IFN-γ is a major regulator of immune functions and has been shown to induce liver-stage Plasmodium elimination both in vitro and in vivo. The molecular mechanism responsible for the restriction of liver-stage Plasmodium downstream of IFN-γ remains uncertain, however. Autophagy, a newly described imm...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Boonhok, Rachasak, Rachaphaew, Nattawan, Duangmanee, Apisak, Chobson, Pornpimol, Pattaradilokrat, Sittiporn, Utaisincharoen, Pongsak, Sattabongkot, Jetsumon, Ponpuak, Marisa
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922146/
https://ncbi.nlm.nih.gov/pubmed/27185909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1525606113
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