Differential immune microenvironments and response to immune checkpoint blockade amongst molecular subtypes of murine medulloblastoma

PURPOSE: Despite significant strides in the identification and characterization of potential therapeutic targets for medulloblastoma (MB), the role of the immune system and its interplay with the tumor microenvironment within these tumors are poorly understood. To address this, we adapted two syngen...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Pham, Christina D., Flores, Catherine, Yang, Changlin, Pinheiro, Elaine M., Yearley, Jennifer H., Sayour, Elias J., Pei, Yanxin, Moore, Colin, McLendon, Roger E., Huang, Jianping, Sampson, John H., Wechsler-Reya, Robert, Mitchell, Duane A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922139/
https://ncbi.nlm.nih.gov/pubmed/26405194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-0713
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