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Does Choice Matter? Reference-Based Alignment for Molecular Epidemiology of Tuberculosis

When using genome sequencing for molecular epidemiology, short sequence reads are aligned to an arbitrary reference strain to detect single nucleotide polymorphisms. We investigated whether reference genome selection influences epidemiological inferences of Mycobacterium tuberculosis transmission by...

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Bibliografiset tiedot
Julkaisussa:J Clin Microbiol
Päätekijät: Lee, Robyn S., Behr, Marcel A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922084/
https://ncbi.nlm.nih.gov/pubmed/27076659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00364-16
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