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Does Choice Matter? Reference-Based Alignment for Molecular Epidemiology of Tuberculosis
When using genome sequencing for molecular epidemiology, short sequence reads are aligned to an arbitrary reference strain to detect single nucleotide polymorphisms. We investigated whether reference genome selection influences epidemiological inferences of Mycobacterium tuberculosis transmission by...
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Publicado no: | J Clin Microbiol |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4922084/ https://ncbi.nlm.nih.gov/pubmed/27076659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00364-16 |
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