Melanocortin-3 receptors in the limbic system mediate feeding-related motivational responses during weight loss

OBJECTIVE: Appetitive responses to weight loss are mediated by a nutrient-sensing neural network comprised of melanocortin neurons. The role of neural melanocortin-3 receptors (MC3R) in mediating these responses is enigmatic. Mc3r knockout mice exhibit a paradoxical phenotype of obesity and reduced...

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Détails bibliographiques
Publié dans:Mol Metab
Auteurs principaux: Mavrikaki, Maria, Girardet, Clemence, Kern, Andras, Faruzzi Brantley, Alicia, Miller, Courtney A., Macarthur, Heather, Marks, Daniel L., Butler, Andrew A.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2016
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921936/
https://ncbi.nlm.nih.gov/pubmed/27408780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.05.002
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