The insect repellent N,N-diethyl-m-toluamide (DEET) induces angiogenesis via allosteric modulation of the M3 muscarinic receptor in endothelial cells

The insect repellent N,N-diethyl-m-toluamide (DEET) has been reported to inhibit AChE (acetylcholinesterase) and to possess potential carcinogenic properties with excessive vascularization. In the present paper, we demonstrate that DEET specifically stimulates endothelial cells that promote angiogen...

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發表在:Sci Rep
Main Authors: Legeay, Samuel, Clere, Nicolas, Hilairet, Grégory, Do, Quoc-Tuan, Bernard, Philippe, Quignard, Jean-François, Apaire-Marchais, Véronique, Lapied, Bruno, Faure, Sébastien
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921870/
https://ncbi.nlm.nih.gov/pubmed/27345502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep28546
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