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An ATP-stabilized inhibitor of the proteasome is a component of the 1500-kDa ubiquitin conjugate-degrading complex.

Proteins conjugated to ubiquitin are degraded by a 26S (1500-kDa) proteolytic complex that, in reticulocyte extracts, can be formed by the association of three factors: CF-1, CF-2, and CF-3. One of these factors, CF-3, has been shown to be the proteasome, a 650-kDa multicatalytic protease complex. W...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Driscoll, J, Frydman, J, Goldberg, A L
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49213/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1317579/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.11.4986
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