Valency and density matter: deciphering impacts of immunogen structures on immune responses against a tumor associated carbohydrate antigen using synthetic glycopolymers

For successful carbohydrate based anti-cancer vaccines, it is critical that B cells are activated to secret antibodies targeting the tumor associated carbohydrate antigens (TACAs). Despite the availability of many TACA based constructs, systematic understanding of the effects of structural features...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Biomaterials
Asıl Yazarlar: Qin, Qian, Yin, Zhaojun, Wu, Xuanjun, Haas, Karen M., Huang, Xuefei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921287/
https://ncbi.nlm.nih.gov/pubmed/27294537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2016.05.050
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