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Physiologic force-frequency in engineered heart muscle by electromechanical stimulation

A hallmark of mature mammalian ventricular myocardium is a positive force-frequency relationship (FFR). Despite evidence of organotypic structural and molecular maturation, a positive FFR has not been observed in mammalian tissue engineered heart muscle. We hypothesized that concurrent mechanical an...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Godier-Furnémont, Amandine F. G., Tiburcy, Malte, Wagner, Eva, Dewenter, Matthias, Lämmle, Simon, El-Armouche, Ali, Lehnart, Stephan E., Vunjak-Novakovic, Gordana, Zimmermann, Wolfram-Hubertus
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921199/
https://ncbi.nlm.nih.gov/pubmed/25985155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.03.055
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