Pharmacokinetics and pharmacogenetics of Gemcitabine as a mainstay in adult and pediatric oncology: an EORTC-PAMM perspective

Gemcitabine is an antimetabolite ranking among the most prescribed anticancer drugs worldwide. This nucleoside analog exerts its antiproliferative action after tumoral conversion into active triphosphorylated nucleotides interfering with DNA synthesis and targeting ribonucleotide reductase. Gemcitab...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Chemother Pharmacol
Egile Nagusiak: Ciccolini, Joseph, Serdjebi, Cindy, Peters, Godefridus J., Giovannetti, Elisa
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer Berlin Heidelberg 2016
Gaiak:
Review Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921117/
https://ncbi.nlm.nih.gov/pubmed/27007129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-016-3003-0
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