Identification and analysis of the gene encoding human PC2, a prohormone convertase expressed in neuroendocrine tissues.

In recent studies we have identified PC2 and PC3, members of a family of serine proteases that are related structurally to subtilisin, and have provided evidence that these are involved in the tissue-specific processing of prohormones and neuropeptides. PC2 is expressed at high levels in the islets...

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Main Authors: Ohagi, S, LaMendola, J, LeBeau, M M, Espinosa, R, Takeda, J, Smeekens, S P, Chan, S J, Steiner, D F
Format: Artigo
Jezik:Inglês
Izdano: 1992
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC49211/
https://ncbi.nlm.nih.gov/pubmed/1594602
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