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Role for serotonin2A (5-HT2A) and 2C (5-HT2C) receptors in experimental absence seizures

Absence seizures (ASs) are the hallmark of childhood/juvenile absence epilepsy. Monotherapy with first-line anti-absence drugs only controls ASs in 50% of patients, indicating the need for novel therapeutic targets. Since serotonin family-2 receptors (5-HT(2)Rs) are known to modulate neuronal activi...

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Detalhes bibliográficos
Publicado no:Neuropharmacology
Main Authors: Venzi, Marcello, David, François, Bellet, Joachim, Cavaccini, Anna, Bombardi, Cristiano, Crunelli, Vincenzo, Di Giovanni, Giuseppe
Formato: Artigo
Idioma:Inglês
Publicado em: Pergamon Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920646/
https://ncbi.nlm.nih.gov/pubmed/27085605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.04.016
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