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Natural Polymorphisms Conferring Resistance to HCV Protease and Polymerase Inhibitors in Treatment-Naïve HIV/HCV Co-Infected Patients in China

BACKGROUND: The advent of direct-acting agents (DAAs) has improved treatment of HCV in HIV co-infection, but may be limited by primary drug resistance. This study reports the prevalence of natural polymorphisms conferring resistance to NS3/4A protease inhibitors and NS5B polymerase inhibitors in tre...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhou, Kali, Liang, Zhiwei, Wang, Charles, Hu, Fengyu, Ning, Chuanyi, Lan, Yun, Tang, Xiaoping, Tucker, Joseph D., Cai, Weiping
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920402/
https://ncbi.nlm.nih.gov/pubmed/27341031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0157438
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