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Fusarium graminearum pyruvate dehydrogenase kinase 1 (FgPDK1) Is Critical for Conidiation, Mycelium Growth, and Pathogenicity

Pyruvate dehydrogenase kinase (PDK) is an important mitochondrial enzyme that blocks the production of acetyl-CoA by selectively inhibiting the activity of pyruvate dehydrogenase (PDH) through phosphorylation. PDK is an effectively therapeutic target in cancer cells, but the physiological roles of P...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gao, Tao, Chen, Jian, Shi, Zhiqi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920349/
https://ncbi.nlm.nih.gov/pubmed/27341107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0158077
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