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Cadherin 2/4 signaling via PTP1B and catenins is crucial for nucleokinesis during radial neuronal migration in the neocortex

Cadherins are crucial for the radial migration of excitatory projection neurons into the developing neocortical wall. However, the specific cadherins and the signaling pathways that regulate radial migration are not well understood. Here, we show that cadherin 2 (CDH2) and CDH4 cooperate to regulate...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Martinez-Garay, Isabel, Gil-Sanz, Cristina, Franco, Santos J., Espinosa, Ana, Molnár, Zoltán, Mueller, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920171/
https://ncbi.nlm.nih.gov/pubmed/27151949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.132456
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