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De novo neurogenesis by targeted expression of atoh7 to Müller glia cells

Regenerative responses in the vertebrate CNS depend on quiescent radial glia stem cells, which re-enter the cell cycle and eventually differentiate into neurons. The entry into the cell cycle and the differentiation into neurons are events of opposite nature, and therefore efforts to force quiescent...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Development
Main Authors: Lust, Katharina, Sinn, Rebecca, Pérez Saturnino, Alicia, Centanin, Lázaro, Wittbrodt, Joachim
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4920165/
https://ncbi.nlm.nih.gov/pubmed/27068106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.135905
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